UFC Vegas 21: Edwards vs. Muhammad (also known as UFC Fight Night 187 and UFC on ESPN+ 45) is set to take place on March 13, 2021, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A UFC Welterweight bout between Leon Edwards and Belal Muhammad is set for the main event of the night and as the event headliner. Misha Cirkunov vs. Ryan Spann for the Light Heavyweight bout will serve as the co-main event.

Check out the announced fight card;

Main card (ESPN+)

Leon Edwards vs. Belal Muhammad for Welterweight Bout ( Main event)

Misha Cirkunov vs. Ryan Spann for Light Heavyweight Bout ( Co-main event)

Dan Ige vs. Gavin Tucker for Featherweight Bout

Jonathan Martinez vs. Davey Grant for Bantamweight Bout

Matheus Nicolau vs. Manel Kape for Flyweight Bout

Eryk Anders vs. Darren Stewart for Middleweight Bout

Preliminary card (ESPN+)

Angela Hill vs. Ashley Yoder for Women's Strawweight Bout

Nasrat Haqparast vs. Rafa García for Lightweight Bout

Charles Jourdain vs. Marcelo Rojo for Featherweight Bout

Rani Yahya vs. Ray Rodriguez for Bantamweight Bout

Cortney Casey vs. JJ Aldrich for Women's Flyweight Bout

Jinh Yu Frey vs. Gloria de Paula for Women's Strawweight Bout

Matthew Semelsberger vs. Jason Witt for Welterweight Bout

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